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Two-port vs four-port measurements

A differential pair is a 4-port device: positive and negative on the near end, positive and negative on the far end. A 2-port VNA can only see one port-pair at a time. That is why labs often take four S2P files (or one S4P) for a single cable or connector.

What a 2-port file contains

Each .s2p holds S11, S21, S12, S22 for one stimulus/response pair, with the unused DUT ports terminated however they were during that sweep (often 50 Ω loads, sometimes open, sometimes the VNA’s other port if you used a fixture).

Those four files are not a complete 4-port S-matrix. Cross terms that were never measured are missing. Transmission mixed-mode (SDD21, SCC21, …) from the four S21 traces is the usual, defensible use. Reflection mixed-mode (SDD11, …) from four S11 traces is an approximation — each S11 saw a different termination on the far-side pair.

When you need a true S4P

Prefer a 4-port VNA (or a 2-port plus a switch matrix that the vendor’s software reassembles) when you need:

  • Accurate SDD11 / SDD22 (return loss of the differential pair)
  • Mode conversion on reflection (SDC11, SCD11)
  • Cascading the DUT with other 4-port networks
  • Fixture removal that uses the full matrix

Four S2Ps as a workflow

If the bench is 2-port only:

  1. Measure the four port-pairs (commonly p13, p14, p23, p24).
  2. Store each as its own dataset with a shared serial and a mixed_mode (or port_pair) parameter.
  3. Confirm polarity mapping before converting.
  4. Publish mixed-mode transmission traces. Treat mixed-mode reflection as approximate unless you also have an S4P.

See Mixed-mode conversion and Mixed-mode reflection.